Endocrine Abstracts

Introduction: Low testosterone serum levels are associated with increased mortality in non-diabetic males. However, knowledge about the association between male hypogonadism and mortality among type 2 diabetic (T2DM) men is limited due to short follow-up periods in the few existing studies.Objective: To assess the association between hypogonadism and mortality in diabetic men.Material and methods: 263 unselected men with T2DM (mean...

Introduction: Graves’ orbitopathy (GO) is the most common extrathyroidal manifestation of Graves’ disease. The first-line treatment are intravenous corticoids in active moderate-severe GO. Tocilizumab is a humanized monoclonal antibody against the IL-6 receptor which has been approved for the treatment of rheumatoid arthritis and is in its research stage for patients with corticosteroid-refractory GO.Objectives: To assess the experience with to...

Prostate cancer (PCa) represents the most diagnosed tumour pathology in developed countries among men population. The main pharmacological approach to treat this pathology is based on the blockade of the androgen receptor signalling pathway, commonly known as androgen-deprivation therapy. However, some of the patients does no longer respond to this therapy, therefore developing castration-resistant prostate cancer (CRPC), the most aggressive phenotype of this pathology, which ...

Introduction: In patients receiving Parenteral Nutritcion (PN), hyponatremia is associated with increased in-hospital mortality. Our objective was to evaluate the influence of volemic classification (hypovolemia, euvolemia or hypervolemia) on in-hospital mortality in patients receiving PN presenting hyponatremia.Methods: Prospective, non-interventional, multicenter study in 19 Spanish hospitals. 543 non-critical patients receiving PN were recruited. Hypo...